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Project information
Molecular pathogenesis of alimentary infection by tick-borne encephalitis virus.

Investor logo
Project Identification
GA23-07160S
Project Period
1/2023 - 12/2025
Investor / Pogramme / Project type
Czech Science Foundation
  • Standard Projects
MU Faculty or unit
Faculty of Science
Cooperating Organization
Biological Centre of the ASCR, v. v. i.
  • Responsible person RNDr. Jiří Salát, Ph.D.

Here, we propose a new 3-year research project to investigate several critical aspects of the pathogenesis of alimentary TBE. The cellular and molecular factors underlying TBEV intestinal infection, pathology, inflammatory changes, and factors involved in the TBEV infection via the digestive tract are currently poorly understood. It is critical to understand the mechanisms involved in the development and physiopathology of this largely neglected TBEV mode of infection. We will use an innovative combination of the most advanced experimental approaches and state-of-the-art in vitro and in vivo models to investigate this important, but poorly understood aspect of TBE.

Publications

Total number of publications: 5

2025

2024

2023

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