Project information
European Human Biomonitoring Initiative
(HBM4EU)
- Project Identification
- 733032
- Project Period
- 1/2017 - 6/2022
- Investor / Pogramme / Project type
-
European Union
- Horizon 2020
- Health, demographic change and wellbeing (Societal Challenges)
- MU Faculty or unit
-
Faculty of Science
- prof. RNDr. Jana Klánová, Ph.D.
- Mgr. Ondřej Adamovský, Ph.D.
- Lola Murielle Bajard ép.Esner, Ph.D.
- prof. RNDr. Luděk Bláha, Ph.D.
- doc. RNDr. Pavel Čupr, Ph.D.
- Elena Dominguez Romero, PhD.
- Mgr. Klára Komprdová, Ph.D.
- Ing. Štěpán Koudelka, Ph.D.
- RNDr. Ondřej Májek, Ph.D.
- Lisa Emily Melymuk, Ph.D.
- Chander Kant Negi, Ph.D.
- Mgr. Ondřej Ngo, Ph.D.
- Ing. Šárka Palátová, Ph.D.
- Veronika Janina Schacht, Ph.D.
- Mgr. Libor Šulc, Ph.D.
- Jakub Vinkler, DiS.
- Chiara Maria Vitale, PhD
- Cooperating Organization
-
Institute of Experimental Medicine of the ASCR, v. v. i.
- Responsible person MUDr. Radim Šrám, DrSc.
- Responsible person prof. MUDr. Milena Králíčková, Ph.D.
- Responsible person prof. Ing. Jana Hajšlová, CSc.
- Responsible person Ing. Adéla Fraňková, Ph.D.
- Responsible person Gorazd B. Stokin
- Responsible person RNDr. Ondřej Májek, Ph.D.
- Responsible person Marike Kolossa-Gehring
The overarching goal of the European Human Biomonitoring Initiative is to generate knowledge to inform the safe management of chemicals and so protect human health. We will use human biomonitoring to understand human exposure to chemicals and resulting health impacts and will communicate with policy makers to ensure that our results are exploited in the design of new chemicals policies and the evaluation of existing measures.
Key objectives include:
- Harmonizing procedures for human biomonitoring across 26 countries, to provide policy makers with comparable data on human internal exposure to chemicals and mixtures of chemicals at EU level;
- Linking data on internal exposure to chemicals to aggregate external exposure and identifying exposure pathways and upstream sources. Information on exposure pathways is critical to the design of targeted policy measures to reduce exposure;
- Generating scientific evidence on the causal links between human exposure to chemicals and negative health outcomes; and
- Adapting chemical risk assessment methodologies to use human biomonitoring data and account for the contribution of multiple external exposure pathways to the total chemical body burden.
We will achieve these objectives by harmonizing human biomonitoring initiatives in 26 countries, drawing on existing expertise and building new capacities. By establishing National Hubs in each country to coordinate activities, we will create a robust Human Biomonitoring Platform at European level. This initiative contributes directly to the improvement of health and well-being for all age groups, by investigating how exposure to chemicals affects the health of different groups, such as children, pregnant women, foetuses and workers. We will also investigate how factor such as behavior, lifestyle and socio-economic status influence internal exposure to chemicals across the EU population. This knowledge will support policy action to reduce chemical exposure and protect
health.
Publications
Total number of publications: 51
2024
-
Phthalates and substitute plasticizers: Main achievements from the European human biomonitoring initiative HBM4EU
International Journal of Hygiene and Environmental Health, year: 2024, volume: 259, edition: June 2024, DOI
2023
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Application of AOPs to assist regulatory assessment of chemical risks - Case studies, needs and recommendations
Environmental Research, year: 2023, volume: 217, edition: January 2023, DOI
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Assessment of exposure to pesticide mixtures in five European countries by a harmonized urinary suspect screening approach
International Journal of Hygiene and Environmental Health, year: 2023, volume: 248, edition: March 2023, DOI
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Cognitive Performance and Exposure to Organophosphate Flame Retardants in Children: Evidence from a Cross-Sectional Analysis of Two European Mother-Child Cohorts
Toxics, year: 2023, volume: 11, edition: 11, DOI
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Current exposure to phthalates and DINCH in European children and adolescents - Results from the HBM4EU Aligned Studies 2014 to 2021
International Journal of Hygiene and Environmental Health, year: 2023, volume: 249, edition: April 2023, DOI
-
Current-use pesticide exposure pathways in Czech adults and children from the CELSPAC-SPECIMEn cohort
Environment International, year: 2023, volume: 181, edition: November 2023, DOI
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Effects of pesticide exposure on oxidative stress and DNA methylation urinary biomarkers in Czech adults and children from the CELSPAC-SPECIMEn cohort
Environmental Research, year: 2023, volume: 222, edition: April 2023, DOI
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ELIXIR and Toxicology: a community in development [version 2; peer review: 2 approved]
F1000Research, year: 2023, volume: 10, DOI
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Exposure to flame retardants in European children - Results from the HBM4EU aligned studies
International Journal of Hygiene and Environmental Health, year: 2023, volume: 247, edition: January 2023, DOI
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From science to policy: How European HBM indicators help to answer policy questions related to phthalates and DINCH exposure
International Journal of Hygiene and Environmental Health, year: 2023, volume: 247, edition: January 2023, DOI