Department of Experimental Biology

Articles

• Biochemical and Computational Characterization of Haloalkane Dehalogenase Variants Designed by Generative AI: Accelerating the SN2 Step

  GELFAND Natalia OREL Vojtěch CUI Wenqiang DAMBORSKÝ Jiří LI Chenglong PROKOP Zbyněk XIE Wen Jun WARSHEL Arieh

  Article in Periodical

  Journal of the American Chemical Society, year: 2025, volume: 147, edition: 3, DOI

• Breaking boundaries: role of the brain barriers in metastatic process

  NASIM Izadi MARYAM Shahidian Akbar SOLÁR Peter KLARA Mrazova HAŠANOVÁ Klaudia MARTIN Bartosik ZAMANI Alemeh TOMAS Kazda SHAHIDIAN AKBAR Maryam ROMAN Hrstka MRÁZOVÁ Klára JOUKAL Marek BARTOŠÍK Martin KAZDA Tomáš HRSTKA Roman JOUKAL Marek

  Article in Periodical

  FLUIDS AND BARRIERS OF THE CNS, year: 2025, volume: 22, edition: 1, DOI

• Brucella microti and Rodent-Borne Brucellosis: A Neglected Public Health Threat

  RUDOLF Ivo KEJÍKOVÁ Romana KOSOY Michael HUBÁLEK Zdeněk MRAVCOVÁ Kristína ŠIKUTOVÁ Silvie WHATMORE Adrian M SASCHA Al Dahouk

  Article in Periodical

  Zoonoses and Public Health, year: 2025, volume: 72, edition: 1, DOI

• Cancer stem cells: Masters of all traits

  LECK Lionel Y. W. EL-AZIZ Yomna S. Abd MCKELVEY Kelly J. PARK Kyung Chan SAHNI Sumit LANE Darius J. R. ŠKODA Jan JANSSON Patric J.

  Article in Periodical

  Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, year: 2025, volume: 1871, edition: 3, DOI

• Depleting chemoresponsive mitochondrial fission mediator DRP1 does not mitigate sarcoma resistance

  BOŘÁNKOVÁ Karolína SOLNÝ Matyáš KRCHNIAKOVÁ Mária ŠKODA Jan

  Article in Periodical

  Life Science Alliance, year: 2025, volume: 8, edition: 2, DOI

• Development and Discovery of a Selective Degrader of Casein Kinases 1 δ/ε

  HAAG Adrian NEMEC Vaclav JANOVSKÁ Pavlína BARTOŠÍKOVÁ Jana ADHIKARI Bikash MUELLER Juliane SCHWALM Martin P ČADA Štěpán OHMAYER Uli DAUB Henrik KIM Yeojin BORN Florian WOLF Elmar BRYJA Vítězslav KNAPP Stefan

  Article in Periodical

  Journal of Medicinal Chemistry, year: 2025, volume: 68, edition: 1, DOI

• Development of a porcine model of skin and soft-tissue infection caused by Staphylococcus aureus, including methicillin-resistant strains suitable for testing topical antimicrobial agents

  RAŠKA Filip LIPOVÝ Břetislav KOBZOVÁ Šárka VACEK Lukáš JAROŠOVÁ Rea POLAŠTÍK KLEKNEROVÁ Dominika MATIAŠKOVÁ Katarína MAKOVICKÝ Peter VÍCENOVÁ Monika JEKLOVÁ Edita PANTŮČEK Roman FALDYNA Martin JANDA Lubomír

  Article in Periodical

  Animal Models and Experimental Medicine, year: 2025, volume: 8, edition: 3, DOI

• Development of Lentil Flour-Enriched Chocolate Matrices for 3D Printing: Impact on Bioactivity, Rheology, and Texture

  DORDEVIĆ Dani TĚŠÍKOVÁ Karolína KOUDELKOVÁ MIKOLÁŠKOVÁ Hana MARTÍNEZ-MONZÓ Javier MATAS Adrián DORDEVIĆ Simona KUSHKEVYCH Ivan

  Article in Periodical

  Food and Bioprocess Technology, year: 2025, DOI

• Discovery of new inhibitors of nuclease MRE11

  NIKULENKOV Fedor CARBAIN Benoit Jean-Pierre BISWAS Raktim HAVEL Štěpán PROCHÁZKOVÁ Jana SISÁKOVÁ Alexandra ZACPALOVÁ Magdaléna CHAVDAROVA Melita MARINI PALOMEQUE María Victoria VŠIANSKÝ Vít WEISOVÁ Veronika SLÁVIKOVÁ Kristína BIRADAR Dhanraj Omprakash KHIRSARIYA PrashantKumar VITEK Marco SEDLAK David BARTUNEK Petr DANIEL Lukáš BREZOVSKÝ Jan DAMBORSKÝ Jiří PARUCH Kamil KREJČÍ Lumír

  Article in Periodical

  European Journal of Medicinal Chemistry, year: 2025, volume: 285, edition: March, DOI

• Electrochemical Detection of BRAF V600E Mutation in a Liquid Biopsy Format: LAMPing the Way to an Improved Diagnostics and Treatment

  MORÁŇOVÁ Ludmila STRMISKOVÁ Johana ONDRÁŠKOVÁ Kateřina BARDELČÍK Miroslav CWIK Matouš KISS Igor HRSTKA Roman BARTOŠÍK Martin

  Article in Periodical

  ADVANCED MATERIALS TECHNOLOGIES, year: 2025, DOI