prof. RNDr. Viktor Brabec, DrSc.

2024

• Dicobalt(II) helices kill colon cancer cells <i>via</i> enantiomer-specific mechanisms; DNA damage or microtubule disruption

  SONG Hualong KOSTRHUNOVÁ Hana ČERVINKA Jakub MACPHERSON Julie MALINA Jaroslav RAJAN Teena PHILLIPS Roger POSTINGS Miles SHEPHERD Samantha ZHANG Xuejian BRABEC Viktor ROGERS Nicola J SCOTT Peter

  Article in Periodical

  Chemical Science, year: 2024, DOI

• New cyclometalated Ru(ii) polypyridyl photosensitizers trigger oncosis in cancer cells by inducing damage to cellular membranes

  ČERVINKA Jakub HERNÁNDEZ-GARCÍA Alba BAUTISTA Delia MARKOVÁ Lenka KOSTRHUNOVÁ Hana MALINA Jaroslav KAŠPÁRKOVÁ Jana SANTANA M Dolores BRABEC Viktor RUIZ José

  Article in Periodical

  INORGANIC CHEMISTRY FRONTIERS, year: 2024, volume: -, edition: -, DOI

• NEW PHOTOACTIVABLE RUTHENIUM COMPOUND TRIGGERS ONCOSIS IN CANCER CELLS BY DISRUPTING CELLULAR MEMBRANES

  ČERVINKA Jakub MARKOVÁ Lenka MALINA Jaroslav KAŠPÁRKOVÁ Jana BRABEC Viktor

  Appeared in Conference without Proceedings

  Year: 2024, type: Appeared in Conference without Proceedings

• Targeting CTG repeat expansions in DM1 cells using a supramolecular metal helicate

  ČERVINKA Jakub MALINA Jaroslav KOSTRHUNOVÁ Hana BRABEC Viktor

  Appeared in Conference without Proceedings

  Year: 2024, type: Appeared in Conference without Proceedings

2023

• N-Indolyl diiron vinyliminium complexes exhibit antiproliferative effects in cancer cells associated with disruption of mitochondrial homeostasis, ROS scavenging, and antioxidant activity

  BRESCIANI Giulio ČERVINKA Jakub KOSTRHUNOVÁ Hana BIANCALANA Lorenzo BORTOLUZZI Marco PAMPALONI Guido NOVOHRADSKÝ Vojtěch BRABEC Viktor MARCHETTI Fabio KAŠPÁRKOVÁ Jana

  Article in Periodical

  Chemico-Biological Interactions, year: 2023, volume: 385, edition: November, DOI

• Ruthenium(II)-Tris-pyrazolylmethane Complexes Inhibit Cancer Cell Growth by Disrupting Mitochondrial Calcium Homeostasis

  ČERVINKA Jakub GOBBO Alberto BIANCALANA Lorenzo MARKOVÁ Lenka NOVOHRADSKÝ Vojtěch GUELFI Massimo ZACCHINI Stefano KAŠPÁRKOVÁ Jana BRABEC Viktor MARCHETTI Fabio

  Appeared in Conference without Proceedings

  Year: 2023, type: Appeared in Conference without Proceedings

2022

• Ruthenium(II)-Tris-pyrazolylmethane Complexes Inhibit Cancer Cell Growth by Disrupting Mitochondrial Calcium Homeostasis

  ČERVINKA Jakub GOBBO Alberto BIANCALANA Lorenzo MARKOVÁ Lenka NOVOHRADSKÝ Vojtěch GUELFI Massimo ZACCHINI Stefano KAŠPÁRKOVÁ Jana BRABEC Viktor MARCHETTI Fabio

  Article in Periodical

  Journal of Medicinal Chemistry, year: 2022, volume: 65, edition: 15, DOI

2012

• Platinum-DNA interstrand crosslinks: Molecular determinants of bending and unwinding of the double helix.

  SUCHÁNKOVÁ Tereza KUBÍČEK Karel KAŠPÁRKOVÁ Jana BRABEC Viktor KOZELKA Jiří

  Article in Periodical

  Journal of Inorganic Biochemistry, year: 2012, volume: 108, edition: 1, DOI

2009

• Energetics, conformation and recognition of DNA duplexes modified by methylated analougues of [PtCl(dien)]+

  NOVÁKOVÁ Olga MALINA Jaroslav KAŠPÁRKOVÁ Jana HALÁMIKOVÁ Anna BERNARD Vladan INTINI Francesco NATILE Giovanni BRABEC Viktor

  Article in Periodical

  Chemistry – A European Journal, year: 2009, volume: 2009, edition: 15

2008

• Binding of mismatch repair protein MutS to mispaired DNA adducts of intercalating ruthenium(II) arene complexes

  CASTELLANO-CASTILLO Maria KOSTRHUNOVA Hana MARINI PALOMEQUE María Victoria KAŠPÁRKOVÁ Jana SADLER Peter J. MALINGE Jean-Marc BRABEC Viktor

  Article in Periodical

  Journal of Biological Inorganic Chemistry, year: 2008, volume: 13, edition: 6