RNDr. Bořivoj Vojtěšek, DrSc.

Field of study: Biochemistry

The study of molecular regulation mechanisms using proteomics tools – graduate 2019
Targeted proteomics, a new approach for protein quantitation in tumor biology – graduate 2018
Molecular mechanisms of metastasis: Integrated genomics and proteomics approaches – graduate 2016

Characterization of new organometallic compounds with potential anticancer effects – graduate 2021

Novel methods of p53 protein-DNA interaction studies based on chemical modification, fluorescence and electrochemical analysis – graduate 2018

Study of molecular-biological markers and their functional relationship in brest tumors – graduate 2008

Studium interakcí proteinové rodiny p53 v normálních a nádorových buňkách – ongoing study
Study of molecular and functional mechanism of novel cytostatics (derivates of polymethinium salts) – graduate 2022
p63 expression and signaling in cancer – graduate 2022

Role of lithocholic acid-induced cell signalling in oesophageal cancer progression model – graduate 2023
An analysis of the interactions of adenovirus vectors and human cytomegalovirus with host cells – graduate 2020

The role of AGR2 and AGR3 proteins in cancer cell in response to stress conditions – graduate 2017
Analysis of conformation-specific interaction of Hsp70 chaperone with Tomm34 cochaperone – graduate 2016
Molecular complexity of p63 in cancer – graduate 2016
Structural and functional analysis of Hsp70/Hsp90 TPR co-chaperones – graduate 2015
Analysis of the Hsp70/Hsp90 chaperone system in cancer cells – graduate 2014
Study of cisplatin derivatives effects on cancer cell – graduate 2010
The role of inhibitors of cyclin dependent kinases in induction of transcription stress and their effects on tumor suppressor p53 and its homolog proteins – graduate 2008

Electrochemical methods for detection of DNA-protein interactions and for monitoring of DNA enzymatic processing – graduate 2018

The analysis of AGR2 and AGR3 roles in tumor cells and determination of their expression in selected cancer tissues – graduate 2014
The role of p63 isoforms in malignant transformation of the cell – graduate 2014
Regulation of expression of selected viral and human gene participating in signal pathways controlled by p53 protein in cancer cells – graduate 2010
Interaction of p53 protein and its homolgues with DNA and their role in malignant transformation – graduate 2009