Informace o projektu
Career Restart - Stem Cell-Based Models of Neurodegeneration
- Kód projektu
- MUNI/R/1697/2020
- Období řešení
- 1/2021 - 5/2023
- Investor / Programový rámec / typ projektu
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Masarykova univerzita
- Grantová agentura MU
- CAREER RESTART
- Fakulta / Pracoviště MU
- Lékařská fakulta
My career was interrupted in May 2019 and despite I did my best to keep in touch with research and my team, I only had limited time to focus on all previous research activities. The current “Career restart” grant would allow me to again fully engage in the research of neurobiology and neurodegeneration that I pursued before.
Cíle udržitelného rozvoje
Masarykova univerzita se hlásí k cílům udržitelného rozvoje OSN, jejichž záměrem je do roku 2030 zlepšit podmínky a kvalitu života na naší planetě.
Publikace
Počet publikací: 9
2024
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A closed 3D printed microfluidic device for automated growth and differentiation of cerebral organoids from single-cell suspension
Biotechnology Journal, rok: 2024, ročník: 19, vydání: 8, DOI
2023
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Cerebral organoids derived from patients with Alzheimer´s disease with PSEN1/2 mutations have defective tissue patterning and altered development
CELL REPORTS, rok: 2023, ročník: 42, vydání: 11, DOI
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Glioblastoma and cerebral organoids: development and analysis of an in vitro model for glioblastoma migration
MOLECULAR ONCOLOGY, rok: 2023, ročník: 17, vydání: 4, DOI
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MicroRNA Profiling of Self-Renewing Human Neural Stem Cells Reveals Novel Sets of Differentially Expressed microRNAs During Neural Differentiation In Vitro
Stem Cell Reviews and Reports, rok: 2023, ročník: 19, vydání: 5, DOI
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Single Cerebral Organoid Mass Spectrometry of Cell-Specific Protein and Glycosphingolipid Traits
Analytical Chemistry, rok: 2023, ročník: 95, vydání: 6, DOI
2022
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Geometric Control of Cell Behavior by Biomolecule Nanodistribution
ACS BIOMATERIALS SCIENCE & ENGINEERING, rok: 2022, ročník: 8, vydání: 11, DOI
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Human iPSC-Derived Neural Models for Studying Alzheimer’s Disease: from Neural Stem Cells to Cerebral Organoids
Stem Cell Reviews and Reports, rok: 2022, ročník: 18, vydání: 2, DOI
2021
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Generation of six human iPSC lines from patients with a familial Alzheimer's disease (n=3) and sex- and age-matched healthy controls (n=3)
Stem cell research, rok: 2021, ročník: 53, vydání: May 2021, DOI
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Generation of three human iPSC lines from patients with a spontaneous late-onset Alzheimer's disease and three sex- and age-matched healthy controls
Stem cell research, rok: 2021, ročník: 53, vydání: May 2021, DOI