Hypoxia/Hif1α Prevents Premature Neuronal Differentiation of Neural Stem Cells Through the Activation of Hes1
Stem Cell Res. 2020 May;45:101770 ABSTRACT: Embryonic neural stem cells (NSCs), comprising neuroepithelial and radial glial cells, are indispensable precursors of neurons and glia in the mammalian developing brain. Since the process of neurogenesis occurs in a hypoxic environment, the … Read More