Phytochemical S-methyl-L-cysteine sulfoxide from Brassicaceae: a key to health or a poison for bees?

Phytochemical S-methyl-L-cysteine sulfoxide from Brassicaceae: a key to health or a poison for bees?
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Abstract: Intensive agricultural practices impact the health and nutrition of pollinators like honey bees (Apis mellifera). Rapeseed (Brassica napus L.) is widely cultivated, providing diverse nutrients and phytochemicals, including S-methyl-L-cysteine sulfoxide (SMCSO). While the nutritional impact of rapeseed on bees … Read More

Linking planar polarity signalling to actomyosin contractility during vertebrate neurulation

Linking planar polarity signalling to actomyosin contractility during vertebrate neurulation
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Abstract Actomyosin contractility represents an ancient feature of eukaryotic cells participating in many developmental and homeostasis events, including tissue morphogenesis, muscle contraction and cell migration, with dysregulation implicated in various pathological conditions, such as cancer. At the molecular level, actomyosin … Read More

Modeling seasonal immune dynamics of honey bee (Apis mellifera L.) response to injection of heat-killed Serratia marcescens

Modeling seasonal immune dynamics of honey bee (Apis mellifera L.) response to injection of heat-killed Serratia marcescens
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Our data demonstrate increased antimicrobial activity at transcriptional and functional levels in summer and winter workers after injection, with a stronger immune response in winter bees. On the other hand, an increase in hemocyte concentration was observed only in the … Read More

Unveiling vertebrate development dynamics in Xenopus laevis using micro-CT imaging

Unveiling vertebrate development dynamics in Xenopus laevis using micro-CT imaging
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Findings This study utilized micro–computed tomography (micro-CT), a noninvasive 3-dimensional (3D) imaging technique with micrometer-scale resolution, to explore the developmental dynamics and morphological changes in Xenopus laevis. Our approach involved generating high-resolution images and computed 3D models of developing Xenopus … Read More

Characterization of Aspergillus fumigatus secretome during sublethal infection of Galleria mellonella larvae

Characterization of Aspergillus fumigatus secretome during sublethal infection of Galleria mellonella larvae
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Introduction: The fungal pathogen Aspergillus fumigatus can induce prolonged colonization of the lungs of susceptible patients, resulting in conditions such as allergic bronchopulmonary aspergillosis and chronic pulmonary aspergillosis. Hypothesis: Analysis of the A. fumigatus secretome released during sub-lethal infection of … Read More

Vigour-related traits of gibel carp (Carassius gibelio): do they represent reproduction-associated costs facilitating the coexistence of asexual and sexual forms?

Vigour-related traits of gibel carp (Carassius gibelio): do they represent reproduction-associated costs facilitating the coexistence of asexual and sexual forms?
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The coexistence of sexual and asexual lineages is rarely documented in vertebrates. Various ecological and evolutionary mechanisms have been proposed to explain their stable coexistence. Gibel carp (Carassius gibelio), a highly invasive freshwater fish in Europe, is one such example … Read More

New article! 🎉: Proteomic Analysis of Ascitic Extracellular Vesicles Describing Tumor Microenvironment and Predicting Patient Survival in Ovarian Cancer

New article! 🎉: Proteomic Analysis of Ascitic Extracellular Vesicles Describing Tumor Microenvironment and Predicting Patient Survival in Ovarian Cancer
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Happy to announce that our latest article „Proteomic Analysis of Ascitic Extracellular Vesicles Describing Tumor Microenvironment and Predicting Patient Survival in Ovarian Cancer„, has just been published in Journal of Extracellular Vesicles! 🎉 This groundbreaking research delves into the intricate … Read More

Multifunctional graphene quantum dots: A therapeutic strategy for neurodegenerative diseases by regulating calcium influx, crossing the blood-brain barrier and inhibiting Aβ-protein aggregation

Multifunctional graphene quantum dots: A therapeutic strategy for neurodegenerative diseases by regulating calcium influx, crossing the blood-brain barrier and inhibiting Aβ-protein aggregation
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Abstract Multifunctional nanoparticles could be the hallmark for the treatment of neurodegenerative diseases. Dissociation of protein aggregates causing neuronal damage and transfer of specific drugs which can downregulate neuronal excitotoxicity by inhibiting glutamatergic N-Methyl-d-Aspartate-receptors (NMDA) and then reducing calcium influx … Read More

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