Stáhněte si náš informační leták...

Nejnovější publikace z našeho oddělení

Characterization of Heterorhabditis bacteriophora response to insect-derived and non-biological stimuli: Insights into nematode recovery and released proteins
with Žádné komentáře

Highlights: The study examines H. bacteriophora recovery to active parasitism upon host contact. Host and non-biological stimuli trigger recovery and release of secreted proteins. Secretomes of nematodes responding to various activation materials were identified. Insect materials induce the release of proteins key … Read More

Phytochemical S-methyl-L-cysteine sulfoxide from Brassicaceae: a key to health or a poison for bees?
with Žádné komentáře

Abstract: Intensive agricultural practices impact the health and nutrition of pollinators like honey bees (Apis mellifera). Rapeseed (Brassica napus L.) is widely cultivated, providing diverse nutrients and phytochemicals, including S-methyl-L-cysteine sulfoxide (SMCSO). While the nutritional impact of rapeseed on bees … Read More

Linking planar polarity signalling to actomyosin contractility during vertebrate neurulation
with Žádné komentáře

Abstract Actomyosin contractility represents an ancient feature of eukaryotic cells participating in many developmental and homeostasis events, including tissue morphogenesis, muscle contraction and cell migration, with dysregulation implicated in various pathological conditions, such as cancer. At the molecular level, actomyosin … Read More

Modeling seasonal immune dynamics of honey bee (Apis mellifera L.) response to injection of heat-killed Serratia marcescens
with Žádné komentáře

Our data demonstrate increased antimicrobial activity at transcriptional and functional levels in summer and winter workers after injection, with a stronger immune response in winter bees. On the other hand, an increase in hemocyte concentration was observed only in the … Read More

Carboxy-terminal polyglutamylation regulates signalling and phase separation of the Dishevelled protein
with Žádné komentáře

Abstract Polyglutamylation is a reversible posttranslational modification that is catalyzed by enzymes of the tubulin tyrosine ligase-like (TTLL) family. Here, we found that TTLL11 generates a previously unknown type of polyglutamylation that is initiated by the addition of a glutamate … Read More

Efficient cloning of linear DNA inserts (ECOLI) into plasmids using site-directed mutagenesis
with Žádné komentáře

This study introduces a novel cost-effective technique for cloning of linear DNA plasmid inserts, aiming to address the associated expenses linked with popular in vitro DNA assembly methods. Specifically, we introduce ECOLI (Efficient Cloning Of Linear Inserts), a method utilizing … Read More

Fotky z laboratoří našeho oddělení

Výzkumné týmy